If you have abrasive particles in the air from milling, you will want to periodically clean the mechanical parts like the lead screw and anti-backlash nuts. After cleaning the parts, all of the high friction parts that will be in constant contact, lubricating the parts with oils, grease or other lubricants. If the part is of steel material, that material will definitely need to be oiled, greased or lubricated so minimal oxidation will affect the exterior of the steel parts.
The anti-backlash nut is made of Delrin, so petroleum chemicals like oils, grease or lubricants are ok to use. Abrasive particles may affect the anti-backlash nut over time; however, the spring and bushing of the anti-backlash nut will provide extensive use regardless of the wear.
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If using a grease how does one protect leadscrews and rails from corian dust etc.