Hi, is it possible to operate red USB controller with Mach4? What plugins do I need? Thank you.

No, the red mach3 USB controller will only work with mach3, you will need the pokeys57cnc. This controller will work with mach3 or mach4. Here is a link: https://www.buildyourcnc.com/item/electronicsAndMotors-electronic-component-breakout-Mach4-mach3-USB-ethernet-Board