Generally, you’ll need to check what control software will need to be used with the CNC router. Our machines use industry standard electronics and control software that is nonproprietary so you can use just about any software out there with our machines.
Specifically, what software are you planning on using?
I'm searching for the best one,I think that I have to learn more about that in order to be able to make the right decision.
If you are using a computer running Microsoft Windows, then I would recommend using Mach3 or Mach4. If you prefer Linux, then LinuxCNC is the best control software in my opinion.
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I am using Windows 10 and my Shopbot PRT 4g uses Shopbot's proprietary software https://www.shopbottools.com/support/control-software. How can I determine if the 4th axis you offer will be compatible with my machine?