We typically use a 1/4 microstepping for lead screws, but you want to determine the microstepping only after you determine what resolution you want on that axis of the machine.
Resolution is steps per inch or steps per milimeter
I will go over this using steps/inch:
steps = motor steps x driver microstepping
inch = the amount of travel with one full stepper motor rotation
In the case of our 1/2" 5 start 10 TPI lead screw, the axis will travel .5 inches with one stepper motor rotation.
Let's use 1/4 microstepping (4 microsteps for each stepper motor step)
(200 steps x 4) / .5 inches =
800 steps / .5 inches =
Now let's use 1/2 microstepping (2 mistrosteps)
(200 steps x 2) / .5 inches =
400 steps / .5 inches =
Remember that increasing microsteps, the torque is also reduced, but the smoothness from the motor is increased.
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With a 1/2 lead screw what is the optimal steps for the stepper motor driver 1/16, 1/8, 1/4 etc